Supercritical CO2 extraction of lithospermum


Lithospermum (scientific name: Lithospermum erythrorhizon Zucc.) is a plant belonging to the Comfrey genus of the Boraginaceae. Perennial herb, the roots are rich in purple substances. Stems are usually 1-3, erect, 40-90 cm tall.

The leaves are sessile, ovate-lanceolate to broad-lanceolate, 3-8 cm long and 7-17 mm wide.

The inflorescence has stems and upper branches, 2-6 cm long, and the fruiting period is prolonged. The nutlets are ovoid, milky white or yellowish brown, about 3.5 mm long, smooth and shiny, and the midline of the ventral surface is concave with longitudinal grooves. Flower and fruit period is from June to September.

Distributed in North Korea, Japan and China; in China distributed in Liaoning, Hebei, Shandong, Shanxi, Henan, Jiangxi, Hunan, Hubei, North Guangxi, Guizhou, Sichuan, Shaanxi and Southeast Gansu. Grows on the hillside grassland.

Lithospermum perilla is used as a Chinese medicine with dried roots. It has the functions of cooling blood, activating serum, clearing heat and detoxification, and clearing skin rashes. It can treat heat spot rash, damp-heat yellow bile, vomiting blood, blood, blood in urine, diarrhea, bloody dysentery, heat constipation, burns, eczema, erysipelas and other diseases.

Process parameters

Pulverization degree:100 mesh
Extraction pressure: 14 MPa
Extraction temperature: 45°C
Separation pressure: 6 MPa
Separation temperature: 60°C
Extraction time: 100 min